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ea0099ep359 | Reproductive and Developmental Endocrinology | ECE2024

Klinefelter syndrome (KS) prevalence at invasive prenatal diagnosis (ipd) procedures: a systematic review of the literature

Costantino Francesco , De Vincentis Sara , Chiara Decaroli Maria , Rochira Vincenzo

Introduction: KS prevalence is estimated to range from 0.1-0.2 % in men and actually the estimated frequency is of about 1:500 to 1:1000 men1. However, the real prevalence remains unknown due also to the fact that the disease is often overlooked and undermanaged1.Aim and methods: We performed a systematic literature search including studies published between 1971 and January 2024 to investigate the real prenatal prevalence of KS (in...

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ea0093oc34 | Oral communication 5: Reproductive Endocrinology | EYES2023

Testosterone serum levels in idiopathic male infertility: An epidemiological insight with pathophysiological and clinical consequences

Costantino Francesco , Spaggiari Giorgia , Valentina Leonardo Dalla , Romeo Marilina , Roli Laura , De Santis Maria Cristina , Trenti Tommaso , Granata Antonio , Simoni Manuela , Santi Daniele

Background: Despite male idiopathic infertility is characterized by semen analysis alteration with gonadotropins within reference ranges, it is still considered a functional hypogonadotropic hypogonadism (FHH). This simple definition is fundamental to guide the empirical therapeutic approach of these men. However, the number of studies describing total testosterone serum levels (TT) in male idiopathic infertility is still limited.Objective: To evaluate T...

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Endocrine Abstracts

Klinefelter syndrome (KS) prevalence at invasive prenatal diagnosis (ipd) procedures: a systematic review of the literature

Testosterone serum levels in idiopathic male infertility: An epidemiological insight with pathophysiological and clinical consequences

BiosciAbstracts